Rejuran Treatment

A Rejuran treatment is an injectable procedure using polynucleotides designed to help improve overall skin quality. Rather than adding volume like traditional dermal fillers, this treatment focuses on supporting skin regeneration, cell renewal, and the skin's natural repair processes.

Rejuran is often considered for fine lines, early signs of skin ageing, uneven skin texture, enlarged pores, certain acne scars and delicate areas such as the under-eye area.

On this page, you can learn how Rejuran works, who it may be suitable for, what happens during treatment, how recovery usually feels and when results may become visible.

What is a Rejuran treatment?

A Rejuran treatment is an injectable procedure utilising polynucleotides (PN) aimed at supporting the natural repair processes within the skin.

Polynucleotides are DNA fragments used in aesthetic treatments to help support cell regeneration, tissue repair, and the production of collagen and elastin. This process may gradually improve the underlying structure of the skin.

Rejuran is commonly considered for:

• Fine lines

• Acne scars

• Enlarged pores

• Reduced skin elasticity

• Dull skin

• Skin ageing

Read more about Rejuran polynucleotides.

What are polynucleotides?

Polynucleotides are small DNA fragments used in regenerative aesthetic treatments. In Rejuran, they are injected into the skin to support processes involved in repair and renewal.

They are used to support:

• Cell regeneration

• Skin repair

• Skin barrier support

• Collagen production

• Elastin production

This is why Rejuran is often regarded as a treatment that focuses on improving skin quality and supporting skin regeneration.

What does Rejuran do?

Rejuran aims to support natural skin renewal through biostimulation. The polynucleotides help stimulate fibroblasts, which are cells involved in collagen and elastin production.

This process may gradually improve the skin’s structure without adding artificial volume. Results are usually subtle and develop over time.

Rejuran may help with:

• Improved skin quality

• Enhanced hydration

• Refined skin texture

• Reduction of fine lines

• Support for the skin barrier

• Improvement in acne scarring

• A more even skin texture

For visible result expectations, you can also view Rejuran before and after examples.

Which skin concerns can Rejuran address?

Rejuran may be considered for several skin-quality concerns. Suitability depends on your skin, treatment area and expectations.

Fine lines and early wrinkles

Rejuran is often used for early signs of skin ageing and superficial fine lines.

Acne scarring

By supporting tissue repair, Rejuran may help improve the appearance of certain types of acne scars.

Enlarged pores and uneven texture

As skin quality improves, pores and uneven texture may appear less noticeable.

Dull or tired-looking skin

Some people choose Rejuran when the skin looks dry, dull or less resilient.

Under-eye skin quality

Rejuran can be used carefully under the eyes for fine lines, thin skin and delicate texture concerns.

Read more about Rejuran under the eyes and Rejuran acne scars.

Who is a Rejuran treatment suitable for?

A Rejuran treatment may be suitable for people who want to improve skin quality without adding volume.

It may be considered if you:

• want smoother, better hydrated skin

• have fine lines or early signs of ageing

• have certain acne scarring concerns

• want a more even skin texture

• want to support skin quality as it changes with age

• do not want the volume effect of dermal fillers

A practitioner will assess your skin during a consultation and explain whether Rejuran is suitable for your concern, skin condition and goals.

Read more about Rejuran by age and Rejuran for men.

Does a Rejuran treatment hurt?

Most people find Rejuran manageable, although the treatment can feel uncomfortable because it involves multiple small injections across the treatment area.

Clinics often apply numbing cream before treatment to reduce discomfort. Sensitive areas, such as under the eyes, may still feel more tender than other parts of the face.

Any tenderness should gradually settle after treatment.

How many Rejuran treatments will I need?

A course of multiple Rejuran treatments is usually recommended. One session may not be enough to see a clear change, because the treatment works gradually.

The exact treatment plan depends on:

• age

• skin condition

• treatment area

• skin concern

• previous treatments

• desired level of improvement

After the initial course, maintenance treatments may be advised depending on how your skin responds.

Are two Rejuran sessions enough?

For some people, two sessions may give visible improvement. Others may need more sessions. Your practitioner should create a personalised plan based on your skin and expectations.

If you are unsure why the result is subtle, read more about Rejuran not working as expected.

When will I see results from Rejuran?

Rejuran results are not usually immediate. The skin first needs time to settle after the injections. Improvement then develops gradually as skin repair and collagen stimulation are supported.

Results vary from person to person. Your practitioner can explain what is realistic for your skin concern.

Want to know how long the effect may last? Read how long Rejuran lasts.

Is Rejuran safe?

Rejuran is generally considered a safe treatment when performed by an experienced, qualified practitioner in a clinical environment. However, as with any injectable procedure, there are potential risks and side effects.

When is Rejuran not recommended?

Rejuran may not be suitable if you have:

• an active skin infection

• inflammation in the treatment area

• certain medical conditions

• known sensitivity to any ingredients

• pregnancy or breastfeeding

• a history of complications with injectable treatments

During a consultation, your practitioner should assess your medical history, skin condition and expectations before advising whether treatment is appropriate.

Possible side effects and aftercare

Most side effects associated with Rejuran are mild and temporary.

Common reactions at the injection sites include:

• Redness

• Swelling

• Bruising

• Tenderness

• Small bumps at the injection sites

Read more about Rejuran side effects.

Aftercare advice

Following proper aftercare helps ensure a smooth recovery.

Practitioners typically advise that for the first 24 to 48 hours, you should:

• Avoid intense exercise

• Avoid saunas and steam rooms

• Limit direct sun exposure

• Do not massage the injection sites

• Only apply make-up according to your practitioner's advice

Which areas can be treated?

Rejuran is mainly used in areas where skin quality, texture, hydration and elasticity are the main concerns.

Common treatment areas include:

• face

• cheeks

• under-eye area

• neck

• décolletage

The right treatment area depends on your skin concern and whether Rejuran is the most suitable option.

Rejuran vs Profhilo vs Skinboosters

It can be useful to compare Rejuran with other injectable skin-quality treatments before deciding what fits your skin.

Rejuran is usually chosen for skin repair and texture concerns. Profhilo and skinboosters are more commonly chosen for hydration and skin glow.

Compare Rejuran vs Profhilo in more detail.

Compare Rejuran clinics in the UK

Are you considering a Rejuran treatment? It is important to find a reputable clinic and a qualified practitioner who understands your skin.

You can use Injectablesbooking to compare UK clinics, read patient reviews, and explore treatment options near you. Comparing clinics helps you get a better understanding of practitioner experience, treatment costs, and which clinic best aligns with your aesthetic goals.

Frequently asked questions about Rejuran Treatment