Rejuran Treatment

Tom van Eijk
The contents of this article is medically checked by: Drs. Tom van Eijk

A Rejuran treatment is an injectable procedure using polynucleotides designed to help improve overall skin quality. Rather than adding volume like traditional dermal fillers, this treatment focuses on supporting skin regeneration, cell renewal, and the skin's natural repair processes.

Rejuran is often considered for addressing signs of skin ageing, fine lines, certain types of acne scarring, enlarged pores, and uneven skin texture.

On this page, you can learn more about how a Rejuran treatment works, who it may be suitable for, what to expect during the recovery period, and when you might begin to see results.

Rejuran Treatment

What is a Rejuran treatment?

A Rejuran treatment is an injectable procedure utilising polynucleotides (PN) aimed at supporting the natural repair processes within the skin.

Polynucleotides are DNA fragments used in aesthetic treatments to help support cell regeneration, tissue repair, and the production of collagen and elastin. This process may gradually improve the underlying structure of the skin.

Rejuran is commonly considered for:

  • Fine lines

  • Acne scars

  • Enlarged pores

  • Reduced skin elasticity

  • Dull skin

  • Skin ageing

Read more about Rejuran polynucleotides.

What are polynucleotides?

Polynucleotides are small DNA fragments used in regenerative aesthetic treatments.

They are introduced into the skin to support natural processes associated with:

  • Cell regeneration

  • Skin repair

  • Skin barrier support

  • Collagen production

  • Elastin production

This is why Rejuran is often regarded as a treatment that focuses on improving skin quality and supporting skin regeneration.

What does Rejuran do?

Rejuran aims to support natural skin renewal through biostimulation.

The polynucleotides help stimulate fibroblasts, which are the cells responsible for producing collagen and elastin. This process can help refine the skin's structure without adding artificial volume.

By encouraging skin regeneration, Rejuran may help with:

  • Improved skin quality

  • Enhanced hydration

  • Refined skin texture

  • Reduction of fine lines

  • Support for the skin barrier

  • Improvement in acne scarring

  • A more even skin texture

Which skin concerns can Rejuran address?

Fine lines and wrinkles

Rejuran is frequently used to address early signs of skin ageing and superficial fine lines.

Acne scarring

By supporting tissue regeneration, Rejuran is sometimes recommended to help improve the appearance of certain types of acne scars.

Enlarged pores

As the skin's underlying structure improves, pores may appear more refined and less noticeable.

Reduced skin quality

Individuals with dry, dull, or tired-looking skin often choose Rejuran to help restore a fresher appearance.

The under-eye area

Rejuran can be carefully administered to target fine lines and delicate, thinning skin beneath the eyes.

Who is a Rejuran treatment suitable for?

A Rejuran treatment may be a suitable option for individuals who:

  • Want to improve their skin quality

  • Want to reduce fine lines

  • Have acne scarring concerns

  • Want to achieve a smoother, more even skin texture

  • Want to support their skin as it ages

  • Do not want to add volume, as with dermal fillers

A doctor will assess during a consultation whether the treatment is suitable for your skin condition and aesthetic goals.

Read more about Rejuran by age and Rejuran for men.

How does a Rejuran treatment work?

  • Consultation and skin assessment

  • Preparation and numbing cream

  • The Rejuran injections

  • Immediate aftercare advice

  • Gradual result development

Does a Rejuran treatment hurt?

Most patients find the procedure manageable, though experiences vary. Because the treatment involves multiple small injections across the treatment area, it can be slightly uncomfortable.

To help minimise discomfort, clinics typically apply a topical numbing cream prior to the procedure.

How many treatments will I need?

For the best possible outcome, a course of multiple treatments is usually recommended.

The exact treatment plan will depend on your:

  • Age

  • Skin condition

  • Treatment goals

  • Treatment area

Following the initial treatment course, maintenance treatments may be recommended.

Are 2 Rejuran sessions enough?

For some people, two treatments may already provide visible improvements. For others, additional sessions may be needed.

During your consultation, a practitioner will create a personalised treatment plan based on your skin condition and aesthetic goals.

When will I see results?

Because Rejuran works by stimulating natural skin regeneration, results take time to become visible.

Week 1

Immediately following the treatment, you may experience mild redness, swelling, or small bumps at the injection sites. The final results will not be visible at this stage.

Weeks 2 to 4

As the skin begins to heal, many patients report their skin feeling smoother and more hydrated.

Months 2 to 3

During this period, the effects of increased collagen and elastin production typically become more apparent. The skin may look firmer, more even, and generally refreshed.

Is Rejuran safe?

Rejuran is generally considered a safe treatment when performed by an experienced, qualified practitioner in a clinical environment. However, as with any injectable procedure, there are potential risks and side effects.

When is Rejuran not recommended?

The treatment may not be suitable if you have:

  • Active skin infections

  • Inflammation in the treatment area

  • Certain medical conditions

  • Known hypersensitivity to any of the ingredients

  • Pregnancy or breastfeeding

During a consultation, a practitioner will assess whether the treatment is appropriate and safe for you.

Possible side effects and aftercare

Most side effects associated with Rejuran are mild and temporary. Common reactions at the injection sites include:

  • Redness

  • Swelling

  • Bruising

  • Tenderness

  • Small bumps at the injection sites

Read more about Rejuran side effects.

Aftercare advice

Following proper aftercare helps ensure a smooth recovery. Practitioners typically advise that for the first 24 to 48 hours, you should:

  • Avoid intense exercise

  • Avoid saunas and steam rooms

  • Limit direct sun exposure

  • Do not massage the injection sites

  • Only apply make-up according to your practitioner's advice

Which areas can be treated?

Rejuran is primarily used in areas where skin quality, texture, and elasticity are the main concerns.

The most frequently treated areas include:

  • Face

  • Cheeks

  • Under-eye area

  • Neck

  • Décolletage

Rejuran vs Profhilo vs Skinboosters

It can be helpful to understand how Rejuran compares to other popular injectable treatments.

Feature

Rejuran vs Profhilo vs Skin Boosters

Active ingredient

Rejuran: Polynucleotides

Profhilo: Hyaluronic acid

Skin Boosters: Usually hyaluronic acid

Primary purpose

Rejuran: Skin regeneration and repair

Profhilo: Skin hydration

Skin Boosters: Skin hydration

Skin repair focus

Rejuran: Strong focus

Profhilo: Limited focus

Skin Boosters: Limited focus

Skin regeneration

Rejuran: Yes

Profhilo: No

Skin Boosters: Limited

Volume effect

Rejuran: No

Profhilo: No

Skin Boosters: No

Best suited for

Rejuran: Skin quality concerns and acne scarring

Profhilo: Skin laxity and hydration

Skin Boosters: Improving skin quality and hydration

Compare Rejuran clinics in the UK

Are you considering a Rejuran treatment? It is important to find a reputable clinic and a qualified practitioner who understands your skin.

You can use Injectablesbooking to compare UK clinics, read patient reviews, and explore treatment options near you. Comparing clinics helps you get a better understanding of practitioner experience, treatment costs, and which clinic best aligns with your aesthetic goals.

Compare clinics in United Kingdom

Promoted
Top rated
Hampstead Aesthetics
Hampstead Aesthetics
London, West End Lane 269
Rejuran from
£ 295,00
View profile
Simply Clinics
Simply Clinics
Uxbridge, High Street 18
Rejuran from
£ 290,00
View profile

Frequently asked questions about Rejuran Treatment

How is Rejuran different from skinboosters?

Can Rejuran be used under the eyes?

When should I consider starting Rejuran treatments?

What if I don't see results from Rejuran?

How long does a Rejuran treatment take?

Are there any immediate side effects?

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