Rejuran Recovery & Aftercare

Q: How long does Rejuran recovery take?

Recovery generally takes a few days. Redness, mild swelling, and small papules usually subside within 24 to 72 hours.

Q: Is there downtime after Rejuran?

Yes, but it is minimal. Most people can resume normal daily activities straight away, though visible injection marks may be present for a few days.

Q: Are small bumps normal after treatment?

Yes. Small papules or bumps are a standard reaction to the superficial injections and usually fade within a few days.

Q: When will the redness disappear?

Redness and mild swelling typically fade within a few hours to a few days.

Q: Does the treatment hurt?

Rejuran involves tiny injections, so some areas may feel temporarily tender or uncomfortable, particularly where the skin is thin.

Q: What is the most important aftercare advice?

Use SPF, avoid excessive heat and strenuous exercise, keep the skin clean, and strictly follow your practitioner's aftercare protocol.

Q: Can I go to work after Rejuran?

Usually, yes. However, bear in mind that temporary redness or small bumps may be visible on your face.

Q: Can I exercise after the procedure?

It is best to wait until your skin has settled, as exercise increases blood flow and can temporarily worsen swelling and redness.

Q: When can I wear makeup again?

Avoid wearing makeup whilst the injection points are still open or irritated. Once the skin is calm, makeup can usually be reapplied.

Q: Is recovery different under the eyes?

Yes. Because the skin under the eyes is thinner, swelling, papules, and bruising may be slightly more noticeable in this area.

1 July 2026

The contents of this article is medically checked by:
Drs. Tom van Eijk

Rejuran recovery refers to the period after treatment when the skin settles from the injections and temporary reactions such as redness, mild swelling, injection marks and small papules begin to fade.

Most recovery reactions are short-lived, but the exact timeline can vary depending on the treated area, skin sensitivity, injection technique and aftercare. The skin-quality benefits of Rejuran develop gradually after the initial recovery phase.

If you are new to the treatment, start with the main Rejuran guide before comparing recovery, downtime and aftercare advice.

What to expect immediately after Rejuran

Directly after a Rejuran treatment, temporary injection-related reactions can appear. These are usually linked to the injection points and the way the product is placed into the skin.

Common short-term reactions include:

redness
mild swelling
small bumps or papules
visible injection marks
sensitivity
mild bruising
a warm or tight sensation

These reactions do not always mean something is wrong. The skin usually needs time to settle after injections. However, symptoms should gradually improve rather than worsen.

Rejuran recovery timeline

Recovery after Rejuran usually takes a few days. Redness, mild swelling and small papules often settle within 24 to 72 hours, while bruising may remain visible for longer.

Time after treatment	What to expect
Immediately	Redness, papules, mild swelling and injection marks
First 24 hours	Sensitive skin and visible injection reactions
Days 2–3	Swelling and papules usually begin to settle
Days 4–7	Skin often looks calmer and more even
Weeks 2–4	Early skin-quality changes may become noticeable

Recovery varies per person. Skin type, treated area, injection depth, product placement and individual sensitivity can all influence the healing timeline.

For a separate guide on how long the skin-quality effect may last, see how long Rejuran lasts.

Is there downtime after Rejuran?

Yes, but downtime after Rejuran is usually limited. Many people return to normal daily activities quickly, but redness, papules, swelling or bruising may be visible for a few days.

It is sensible not to schedule treatment immediately before an important meeting, event, photoshoot or holiday. This is especially important if you bruise easily or are treating a visible area such as the under eyes.

Most visible injection reactions fade within a few days, but your clinic should explain what is normal for your treatment area.

When do redness, swelling and papules disappear?

Redness and mild swelling generally fade within a few days. Small papules at the injection sites often disappear within 24 to 72 hours. Bruises may take longer to clear.

Reaction	Usually normal for	Contact a practitioner if
Redness	A few hours to a few days	Redness spreads or worsens
Mild swelling	1 to 3 days	Swelling continues to increase
Papules or bumps	1 to 3 days	Bumps become hard, painful or persistent
Bruising	A few days or longer	Bruising rapidly expands
Sensitivity	Temporarily	Pain continues to increase

If you want more detail on possible reactions, read the guide to Rejuran side effects.

Are small bumps normal after Rejuran?

Small bumps, also called papules, are common after Rejuran. They appear because the product is placed superficially into the skin.

The bumps usually settle as the product disperses into the surrounding tissue. Around thinner areas, such as the under eyes, they may be more noticeable or take slightly longer to fade.

Contact your clinic if the bumps become painful, remain red, feel hard to the touch or last significantly longer than expected.

Normal recovery vs when to seek advice

During recovery, it helps to know the difference between expected injection reactions and symptoms that may need a medical check.

Normal after Rejuran	Seek advice if you experience
Mild redness	Increasing or spreading redness
Mild swelling	Severe or asymmetrical swelling
Small bruises	Rapidly worsening bruising
Temporary sensitivity	Increasing or severe pain
Small papules	Hard bumps that do not settle
Injection marks	Heat, pus, fever or signs of infection

If in doubt, contact the clinic where you were treated. It is better to ask early than to ignore symptoms that are worsening.

Rejuran aftercare checklist

1 Avoid intense exercise until the skin has settled
2 Avoid saunas, steam rooms and excessive heat
3 Use daily broad-spectrum SPF
4 Keep skincare gentle and fragrance-free
5 Avoid retinol, peels and strong active acids temporarily
6 Touch the treated area as little as possible
7 Avoid make-up over open injection points
8 Follow the clinic’s specific aftercare instructions

Rejuran aftercare: what to avoid

Good aftercare can help reduce irritation and support a smoother recovery. Your clinic’s advice should always come first, because aftercare can vary depending on the treated area and injection technique.

Exercise can temporarily increase blood flow and may make redness or swelling more noticeable. Heat from saunas, steam rooms, hot showers or sunbeds can also worsen swelling in the first phase of recovery.

Avoid make-up while injection points are still open or irritated. Once the skin is closed and calm, make-up can usually be applied again. Harsh active skincare, including retinoids and exfoliating acids, should also be avoided temporarily.

How can you support your recovery?

You can support your recovery by keeping the skin calm, using adequate sun protection, temporarily avoiding aggressive skincare products, and strictly following your practitioner’s instructions.

The following can also help:

Staying well-hydrated
Applying daily SPF
Using a mild cleanser
Getting plenty of rest

Please note that while these steps support the healing process, they do not guarantee faster results. Rejuran works gradually, as the treatment focuses on cellular skin repair and collagen stimulation over time.

How can you support recovery after Rejuran?

You can support recovery by keeping the skin calm, using sun protection, avoiding aggressive skincare and following your practitioner’s instructions closely.

The following may help during the first recovery phase:

staying well hydrated
using a mild cleanser
applying SPF daily
avoiding unnecessary touching
allowing enough time before events
getting adequate rest

These steps support the healing process, but they do not guarantee faster results. Rejuran works gradually, because the treatment is focused on skin quality and repair processes rather than instant volume.

Is recovery under the eyes different?

Recovery can be more noticeable under the eyes because the skin in this area is thin and delicate. Swelling, bruising and papules may be easier to see and may take slightly longer to settle than on other facial areas.

The under-eye area also requires careful assessment and precise injection technique. If you are considering treatment in this area, read more about Rejuran under eyes.

When will you see results after Rejuran?

Rejuran results are usually not visible immediately. The skin first needs to recover from the injections. After that, changes in skin quality can develop gradually over the following weeks.

The treatment is not a dermal filler designed to add instant volume. It is used to support skin quality, hydration, texture and repair processes. For more detail on the skin-quality mechanism, see Rejuran collagen stimulation.

Rejuran recovery vs Profhilo recovery

Both Rejuran and Profhilo usually involve short recovery periods, but they work differently and may be chosen for different skin concerns.

Feature	Rejuran	Profhilo
Active ingredient	Polynucleotides	Hyaluronic acid
Papules possible?	Yes	Yes
Swelling	Usually temporary	Usually temporary
Downtime	Usually limited	Usually limited
Main focus	Skin quality and repair support	Hydration and skin laxity
Results	Gradual	Gradual

If you are comparing injectable skin-quality treatments, the guide to Rejuran vs Profhilo explains the differences in more detail.

Is aftercare included in Rejuran treatment?

Aftercare should be part of a professional Rejuran treatment plan. A reputable clinic should explain what reactions to expect, what to avoid, and when to contact them.

Before booking, ask whether the clinic includes aftercare advice, review appointments or follow-up support in the treatment plan. This can affect the total value of the treatment, not just the session price.

For more information about pricing factors, see the Rejuran costs guide.

Compare Rejuran clinics

A smooth recovery starts with a carefully performed treatment, clear aftercare instructions and a clinic that is accessible if you have questions afterwards.

When comparing Rejuran clinics, look beyond price and consider:

practitioner experience and qualifications
medical screening before treatment
clinic aftercare policies
accessibility and follow-up support
patient reviews
clear information about risks and recovery

Patient experiences can help you understand how clinics communicate, manage expectations and support aftercare. You can read more on the Rejuran reviews page, or use the Rejuran doctor selection guide before booking a consultation.