What Age Can You Start Rejuran

What age can you start Rejuran? The best age to start Rejuran depends less on your birthday and more on your skin condition. While Rejuran can be used by adults of different ages, most people consider treatment once early signs of skin ageing, acne scarring or reduced skin quality become noticeable. Your practitioner should assess your skin concerns, medical history and treatment goals before deciding whether Rejuran is suitable.

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Biological age or chronological age: When should you start Rejuran?

The question of when to start a skin-rejuvenating treatment has two answers: a legal framework and a biological indication. Unlike traditional dermal fillers, Rejuran is not designed to add volume. It is a polynucleotide-based skin booster that works by supporting the skin's natural repair processes and stimulating tissue regeneration from within.

What age is Rejuran suitable for? While Rejuran is generally performed on adults aged 18 and over, many aesthetic practitioners consider the ideal age to begin treatment to be between 25 and 30 years old. Around this stage of life, natural collagen production gradually declines, meaning polynucleotide treatments may help support skin regeneration and address the earliest visible signs of skin ageing.

From age 18: The minimum age for treatment

Rejuran is generally intended for adults aged 18 years and over. Although collagen production remains high at this age, treatment may still be appropriate in selected cases, particularly for improving the appearance of atrophic acne scars or uneven skin texture. Suitability should always be determined during a consultation with a qualified medical practitioner, as every patient and skin condition is different.

From age 25: Supporting the skin as collagen production declines

Around the age of 25, gradual biological changes begin to occur within the skin. Research suggests that fibroblast activity slowly decreases, leading to a gradual reduction in natural collagen production over time. This is often the stage when the earliest signs of skin ageing begin to develop. Using Rejuran during this phase is often viewed as a preventative skin rejuvenation approach. Rather than filling existing wrinkles, the treatment aims to support collagen production, strengthen the skin barrier, improve elasticity and help maintain healthier-looking skin as natural ageing progresses. Results vary between individuals and depend on factors such as genetics, lifestyle and overall skin health.

Rejuran by age: Which treatment is most suitable for your skin?

When assessing whether you are a suitable candidate for Rejuran, practitioners look at the biological condition of your skin rather than your chronological age. Age alone does not tell the whole story. For example, someone with significant sun damage or a long history of smoking may have skin that shows more advanced signs of ageing than someone of the same age with healthier skin.

Your twenties and thirties (25–35): Preventative skin rejuvenation and acne scars

During this stage of life, skin renewal remains relatively active, but the first fine lines, dullness and early signs of fatigue may begin to appear. Rejuran is often used to support collagen production, improve skin quality and help maintain a healthy, radiant complexion. If you are comparing different injectable skin treatments, you may also wish to read our guide on Rejuran vs Profhilo to understand which option may best suit your skin goals.

• Specific indication: This age group may also benefit from treatment for persistent acne scars or uneven skin texture. Adults aged 18 and over with atrophic acne scars may be suitable candidates for Rejuran S, a formulation designed to support scar remodelling and improve skin texture through collagen stimulation.

Your forties (35–50): Addressing early loss of elasticity and fine lines

By the age of forty, reduced skin elasticity often becomes more noticeable. The skin may appear duller, recover more slowly from environmental damage and develop increasing fine lines around the eyes and mouth. During this stage, Rejuran may help stimulate fibroblasts to support the production of collagen and elastin, contributing to improved skin firmness, elasticity and overall skin quality.

Age 50 and over: Supporting thinner and drier skin

From the age of 50 onwards, hormonal changes, including menopause, may contribute to thinner, drier and more fragile skin. Rejuran may help improve hydration, skin quality and overall skin texture by supporting the skin's natural regenerative processes. The treatment focuses on improving skin quality rather than adding facial volume, helping to achieve refreshed-looking skin while maintaining natural facial features.

Rejuran treatment guide by age

Is there a maximum age for Rejuran treatment?

There is no strict upper age limit for Rejuran treatment. As long as the skin remains biologically active, it may still respond to polynucleotide therapy and support natural tissue repair. However, suitability depends more on skin quality than chronological age.

In patients with more advanced skin ageing, significant skin laxity or substantial volume loss, Rejuran alone may not achieve the desired outcome. In these cases, a practitioner may recommend combining Rejuran with other aesthetic treatments or, where appropriate, discussing surgical options such as a facelift. The most suitable treatment plan should always be based on an individual assessment of your skin condition, medical history and aesthetic goals. If you would like to compare Rejuran with volume-restoring treatments, see our guide on Rejuran vs fillers.

Important medical considerations and aftercare

Regardless of age, good general health is one of the most important factors when determining whether Rejuran is suitable. Rejuran contains highly purified polynucleotides derived from salmon DNA, which are designed to support the skin's natural repair processes and are considered highly biocompatible. However, there are important contraindications. Rejuran may not be suitable for people with a known fish allergy or for those who are pregnant or breastfeeding. Your medical history should always be discussed during a consultation before treatment.

Aftercare is also an important part of the treatment process. Small papules or raised bumps may appear at the injection sites following treatment and typically settle within 24 to 48 hours. During the first few days, it is advisable to avoid harsh skincare products such as retinoids, exfoliating acids and intensive chemical peels, as these may irritate the treated skin. You can find more information on our pages covering Rejuran side effects and Rejuran recovery.

The overall cost of a Rejuran treatment course varies between clinics and depends on factors such as the practitioner, the product used, the treatment area and the number of sessions required. For more information about pricing factors and average treatment costs, visit our Rejuran costs guide.

Frequently asked questions about what age you can start Rejuran

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