Rejuran vs fillers

Rejuran vs fillers: which treatment suits your skin?
Rejuran and dermal fillers are both injectable treatments, but they are used for different goals. Rejuran is usually chosen for skin quality, fine lines, texture, hydration and gradual skin repair. Fillers are usually chosen when the goal is volume, contour, deeper folds or facial balancing.

This page compares Rejuran and fillers by how they work, what results they may give, downtime, side effects, treatment areas and clinic selection. The right option depends on your skin, facial structure, expectations, medical history and the advice of a qualified practitioner.

Is Rejuran better than fillers?

Rejuran is not automatically better than fillers. The treatments have different purposes. Rejuran is more focused on skin quality and gradual improvement, while fillers are more focused on volume, shape and deeper lines.

Choose Rejuran more often for:

• fine lines;

• thin or delicate-looking skin;

• skin texture;

• under-eye skin quality;

• mild crepiness;

• hydration and skin repair.

• Choose fillers more often for:

• volume loss;

• deeper folds;

• lip enhancement;

• cheek contour;

• jawline definition;

• facial balancing.

If both skin quality and volume loss are present, a practitioner may discuss a combined treatment plan. This should always be personalised.

Results and duration of Rejuran and fillers

Rejuran usually gives gradual skin-quality improvement over a course of treatments. Fillers usually give a more immediate visible change because they add volume or structure.

Results vary per person. The final outcome depends on your skin, facial anatomy, treatment area, product choice, practitioner technique and aftercare.

How does Rejuran work?

Rejuran is an injectable skin-quality treatment based on polynucleotides, often shortened to PN or PDRN. In aesthetic medicine, polynucleotides are discussed for their role in supporting skin repair, hydration, elasticity and texture.

Rejuran is not used like a classic filler. It does not aim to add obvious volume. Instead, it is usually chosen when the goal is gradual improvement in skin quality.

Typical Rejuran treatment areas include:

Rejuran may be useful when the skin looks thin, tired, uneven or less resilient, but a consultation is needed to check whether it is suitable.

How do fillers work?

Dermal fillers are usually based on hyaluronic acid. They are injected to add volume, soften folds, shape facial contours or restore structure in areas where volume has reduced.

Fillers can create a more immediate visible change than Rejuran, but they are not mainly designed for skin repair. Their effect depends on the product used, the area treated and the practitioner’s technique.

Typical filler treatment areas include:

• lips;

• cheeks;

• nasolabial folds;

• marionette lines;

• chin;

• jawline;

• tear troughs, where appropriate.

Fillers should be placed carefully, especially in complex areas such as the under eyes, nose, lips and central face.

Main differences between Rejuran and fillers

Rejuran is better suited to skin-quality concerns. Fillers are better suited to shape, structure and volume concerns.

Rejuran before and after vs filler before and after

Before-and-after photos can help you understand the difference between skin-quality improvement and volume correction. Rejuran before-and-after photos usually focus on texture, fine lines, hydration and overall skin quality. Filler before-and-after photos usually show changes in shape, contour, volume or deeper folds.

Photos should never be treated as a guarantee. Lighting, angles, facial expression, skin type, number of sessions and practitioner technique all affect how results appear.

Risks and side effects

Both Rejuran and fillers can cause temporary side effects. These may include redness, swelling, tenderness, bruising, small bumps or visible injection marks. Most mild reactions settle with time, but the exact recovery varies by person and treatment area.

Fillers require particular care because they are placed to add volume and structure. Rare but serious complications can occur with injectable treatments. Contact your clinic promptly if you have worsening pain, unusual skin colour changes, signs of infection or symptoms that do not improve as expected.

Aftercare and recovery

Always follow the aftercare advice from your clinic. General aftercare after Rejuran or fillers may include:

avoiding intense exercise for a short period;

• avoiding sauna, sunbeds and heat;

• not rubbing or massaging the area unless told to;

• avoiding make-up directly after treatment if advised;

• using gentle skincare;

• protecting the skin from strong sun exposure.

Recovery can vary. Rejuran may leave temporary injection marks or small bumps. Fillers may cause swelling or bruising, especially in areas such as the lips or under eyes.

Cost and clinic selection

The cost of Rejuran and fillers varies by clinic, treatment area, product, number of sessions and practitioner experience. Do not compare only the price per appointment. Compare what is included in the consultation, treatment plan and aftercare.

Rejuran is often planned as a course of sessions. Fillers may be priced by area, product or amount used. This means the total cost can be different even if one session looks cheaper.

Read more about Rejuran cost and choosing a Rejuran practitioner if you want to compare clinics more carefully.

Can you combine Rejuran and fillers?

Rejuran and fillers can sometimes be combined when someone has both skin-quality concerns and volume loss. For example, Rejuran may be discussed for texture and fine lines, while fillers may be discussed for cheeks, lips or deeper folds.

A combined plan is not automatically better. The practitioner should explain which concern is being treated first, how much time is needed between treatments and why the plan suits your face and skin.

Frequently asked questions