How long does Profhilo last?

Tom van Eijk
The contents of this article is medically checked by: Drs. Tom van Eijk

How long does Profhilo last is one of the most common questions people ask before treatment. On average, the visible effect of Profhilo may last around 6 to 12 months, although this varies per person.

Profhilo itself does not remain in the skin for that full period. The hyaluronic acid is gradually broken down by the body, but during that time it may support hydration, skin elasticity and collagen activity. This is why the skin can appear smoother, fresher and better hydrated for several months.

Most people start with two treatments spaced around four weeks apart. After that, a maintenance treatment may be advised to help keep the result stable.

You can also read more about the general Profhilo treatment and compare clinics and practitioners in the UK.

How long does Profhilo stay visible?

Profhilo results are usually visible for around 6 to 12 months. The exact duration depends on your skin quality, age, lifestyle, metabolism and treatment plan.

Question

Short answer

How long does Profhilo last?

Usually around 6–12 months

How many treatments are needed?

Often 2 starting treatments

When do results appear?

Often after 4–6 weeks

When is maintenance needed?

Often after 6–12 months

Is Profhilo permanent?

No

How does Profhilo work in the skin?

Profhilo is an injectable treatment based on a high concentration of hyaluronic acid. Unlike traditional fillers, it is not mainly used to add volume. Instead, it spreads under the skin and may help improve hydration, elasticity and overall skin quality.

Profhilo is often considered for:

  • early skin laxity

  • fine lines

  • dry or dehydrated skin

  • loss of elasticity

  • dull skin texture

It is often described as a bio-remodelling treatment because it supports skin quality rather than changing facial shape.

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Why can the result last longer than the product itself?

Profhilo does not literally stay in the skin for 6 to 12 months. The product is gradually broken down by the body.

The visible effect can last longer because Profhilo may support:

  • skin hydration

  • elasticity

  • smoother skin texture

  • improved skin quality

  • a fresher-looking appearance

This is why some people still notice skin improvement after the hyaluronic acid itself has been mostly absorbed.

When do you see results from Profhilo?

Some people notice that their skin feels more hydrated within a few days. The more visible result usually develops gradually and is often seen after the second treatment.

Many people notice:

  • more glow after 1–2 weeks

  • improved skin texture after several weeks

  • better firmness after the second treatment

  • softer-looking fine lines over time

The result is gradual because skin quality changes take time.

Profhilo result timeline

Moment

What may happen

Day 1–3

Small bumps, swelling or redness may appear

Week 1–2

Skin may feel more hydrated

Week 4

Skin texture may start to improve

After treatment 2

Result is usually more visible

6–12 months

Result gradually reduces

Why are two treatments usually needed?

One Profhilo treatment may not be enough for a longer-lasting result. Many clinics recommend a starting course of two treatments, usually around four weeks apart.

A common plan is:

  • first treatment

  • second treatment after around four weeks

  • maintenance after 6 to 12 months if suitable

People with more mature skin or visible skin laxity may need a different maintenance plan.

What affects how long Profhilo lasts?

Not everyone keeps the result for the same length of time. Duration can be influenced by skin condition, lifestyle and how quickly the body breaks down hyaluronic acid.

Factors that may affect duration include:

  • age

  • smoking

  • sun exposure

  • metabolism

  • intensive exercise

  • skin quality

  • dehydration

  • collagen loss

  • hormonal skin changes

A practitioner can assess your skin and advise how often maintenance may be suitable.

Profhilo maintenance by age

Age

Typical maintenance pattern

30–40

Often once a year

40–55

Often every 6–9 months

55+

May need more regular review

This is only a general guide. The right interval depends on your skin, goals and treatment area.

Profhilo vs fillers: which lasts longer?

Profhilo and fillers have different purposes. Fillers are usually used for volume, contouring or softening deeper folds. Profhilo is mainly used for hydration, elasticity and skin quality.

Treatment

Volume

Hydration

Skin quality support

Typical duration

Profhilo

Low

High

High

Around 6–12 months

Fillers

High

Limited

Limited

Around 6–18 months

Skin boosters

Low

High

Mild

Around 4–9 months

Sculptra

No immediate filler volume

Limited

High

Can last longer

Fillers may remain visible for longer because they add structure or volume. Profhilo usually gives a more subtle skin-quality effect.

Read more about fillers, skin boosters and Sculptra.

Profhilo vs Profhilo Structura

Profhilo Structura is a related treatment designed for deeper tissue support. It may be considered when there is more visible skin laxity or structural change.

Standard Profhilo is mainly used for hydration and skin quality. Profhilo Structura focuses more on support and firmness.

Read more about Profhilo Structura.

Before and after photos of Profhilo

Profhilo picture of SkinSurgery Clinics Den Haag (before)
Profhilo picture of SkinSurgery Clinics Den Haag (after)
These pictures are from SkinSurgery Clinics Den Haag
Profhilo picture of Beautifier Maastricht (before)
Profhilo picture of Beautifier Maastricht (after)
These pictures are from Beautifier Maastricht
Profhilo picture of Prof. Aesthetics (before)
Profhilo picture of Prof. Aesthetics (after)
These pictures are from Prof. Aesthetics
Profhilo picture of Moerman Clinic (before)
Profhilo picture of Moerman Clinic (after)
These pictures are from Moerman Clinic
Profhilo picture of SW Clinic (before)
Profhilo picture of SW Clinic (after)
These pictures are from SW Clinic
Profhilo picture of Prof. Aesthetics (before)
Profhilo picture of Prof. Aesthetics (after)
These pictures are from Prof. Aesthetics

Can Profhilo wear off faster?

Yes. In some people, the result may fade sooner than expected.

This can happen due to:

  • intensive exercise

  • faster metabolism

  • high sun exposure

  • smoking

  • more advanced skin laxity

  • not having maintenance treatment

If skin laxity or volume loss is more advanced, a practitioner may discuss other options such as fillers, skin boosters or collagen-stimulating treatments.

Does Profhilo work less well on older skin?

Profhilo can still be suitable for more mature skin, but expectations should be realistic. When there is significant laxity, deep folds or volume loss, Profhilo alone may not provide enough support.

A practitioner may suggest combining treatments when there is:

  • deeper folding

  • visible volume loss

  • loose skin

  • more advanced collagen loss

The aim should be a natural-looking plan that matches the skin condition.

How often should Profhilo be repeated?

Many people choose maintenance once or twice a year, depending on their skin and goals.

A common schedule is:

  • two starting treatments

  • review after several months

  • maintenance after around 6 to 12 months if needed

The right plan varies by skin type, age, treatment area and response.

Are there side effects or downtime?

After Profhilo, small bumps, redness or swelling can appear at the injection points. These are usually temporary.

Possible side effects include:

  • redness

  • mild swelling

  • small bruises

  • tenderness

  • temporary bumps

Clinics may advise you to avoid intense exercise, heat, sauna and facial massage for a short period after treatment. Always follow the aftercare advice given by your practitioner.

What happens when Profhilo wears off?

When Profhilo wears off, the skin gradually returns to its natural ageing process.

You may notice:

  • less glow

  • reduced hydration

  • fine lines becoming more visible again

  • less firmness

Profhilo does not make the skin age faster after the result fades.

Cost of Profhilo maintenance

Because Profhilo is temporary, some people choose regular maintenance treatments. The cost can vary between clinics and depends on several factors.

These may include:

  • practitioner experience

  • number of sessions needed

  • treatment area

  • product used

  • clinic location

  • whether maintenance is part of a wider treatment plan

Compare clinics carefully and check what is included before booking.

Read more about Profhilo costs and Profhilo offers.

Reviews of Profhilo in the UK

Profhilo love the results Emma explains the procedure from the outset. Takes her time no rushing. Very professional I am always really happy with the results. Highly recommend Emma ❤️
Samantha Stables
Aurora Beauty Aesthetics
9 March 2026 03:03
A brilliant experience as always, loving the new consulting room🕶️ Dr Cei explains the process clearly, always listening to what I want to achieve, and reminding me to ‘trust the process’ I can now clearly see the results of the Profhilo Structura and am very pleased 😍 Next procedure booked 👍 I would highly recommend Dr Cei she is amazing!
suzzanne whiting
Dr Cei Aesthetics
5 March 2026 17:05
I honestly wouldn’t trust anyone else with my aesthetics. Natalie and the girls are absolutely amazing. I’ve been going to them for my Botox, skin pen, Profhilo and Morpheus treatments and the care they give every single time is incredible. Natalie is so knowledgeable, patient and genuinely lovely. She always takes the time to talk everything through proper... Show more »
I honestly wouldn’t trust anyone else with my aesthetics. Natalie and the girls are absolutely amazing. I’ve been going to them for my Botox, skin pen, Profhilo and Morpheus treatments and the care they give every single time is incredible.

Natalie is so knowledgeable, patient and genuinely lovely. She always takes the time to talk everything through properly and makes sure you feel completely comfortable before doing anything. You never feel rushed and she really listens to what you want, which makes such a difference.

The whole team are so kind and welcoming and they always make you feel at ease. For me, it’s about trust and I completely trust them with my face. The results are always natural and exactly what I’m looking for.

I wouldn’t go anywhere else Show less »
Caroline Stephanie Young
Naturally Flawless Aesthetics
5 March 2026 14:02
I recently visited Kate Bell Aesthetics for a HydroFacial with Emma and a Profhilo skin booster treatment with Kate, and the experience was fantastic from start to finish. Emma’s HydroFacial was both relaxing and incredibly thorough – my skin looked brighter, clearer and felt deeply hydrated afterwards. Kate is exceptionally knowledgeable and her clinical ba... Show more »
I recently visited Kate Bell Aesthetics for a HydroFacial with Emma and a Profhilo skin booster treatment with Kate, and the experience was fantastic from start to finish. Emma’s HydroFacial was both relaxing and incredibly thorough – my skin looked brighter, clearer and felt deeply hydrated afterwards. Kate is exceptionally knowledgeable and her clinical background as a nurse practitioner is very reassuring, but she is also warm, personable and genuinely interested in helping clients achieve natural, confidence-boosting results. My Profhilo treatment was carefully explained and I felt completely at ease throughout. The whole team at Kate Bell Aesthetics creates such a calm, professional environment. If you’re considering aesthetic treatments but feel nervous about booking, this clinic is the perfect place to start. Highly recommend. Show less »
5 March 2026 10:10
I can’t recommend Amrita highly enough! I’ve been going to her for the last couple of years and she is absolutely fantastic. She is incredibly knowledgeable, professional and makes you feel completely comfortable and confident in her hands. Being a former dentist gives me total reassurance when it comes to treatments and injections. I’ve had both Botox and P... Show more »
I can’t recommend Amrita highly enough! I’ve been going to her for the last couple of years and she is absolutely fantastic. She is incredibly knowledgeable, professional and makes you feel completely comfortable and confident in her hands.
Being a former dentist gives me total reassurance when it comes to treatments and injections. I’ve had both Botox and Profhilo with her and the results have always been amazing natural, fresh and exactly what I wanted.
She takes the time to explain everything and always advises what will work best for you to achieve the best possible results. I always leave feeling so much more confident and can’t wait for my next treatments. Show less »
4 March 2026 13:01
I recently had Profhilo and Profhilo Structura treatments, and I’m so happy with the results. My skin feels firmer, more hydrated, and naturally refreshed. I’m especially glad I chose to do the treatments with Ald- he made me feel completely comfortable, explained everything clearly, and I felt no pain at all. Highly recommend!
Edvinas Lukšys
goaesthetix
1 March 2026 23:11

Experiences and results

Many people choose Profhilo because the result is usually subtle and natural-looking. The skin may appear more hydrated, smoother and fresher without a clear change in facial volume.

People expecting strong lifting or contouring may need a different or combined treatment plan. Results vary, so a consultation is important before deciding.

Read more about Profhilo reviews, Profhilo before and after photos and why Profhilo may not work as expected for some people.

Myths and facts about Profhilo

Statement

Is it correct?

Profhilo stays in the skin for 12 months

Not exactly

The visible effect may last 6–12 months

Yes, for some people

Profhilo gives volume like fillers

No

Maintenance is often needed

Yes

Profhilo can support skin quality

Yes

Frequently asked questions about Profhilo duration

How long does Profhilo last?

How often should Profhilo be repeated?

When do you see results from Profhilo?

Is Profhilo permanent?

Do fillers last longer than Profhilo?

Can exercise make Profhilo wear off faster?

What happens if you stop Profhilo?

Is Profhilo suitable after 50?

Compare Profhilo clinics in the UK

Compare clinics and practitioners for Profhilo treatment in the UK. Look at reviews, treatment information, before and after photos and consultation options before booking.

Compare clinics in United Kingdom

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