Profhilo Structura

1 July 2026
Tom van Eijk
The contents of this article is medically checked by: Drs. Tom van Eijk

Profhilo Structura is an injectable hyaluronic acid treatment developed for selected superficial fat compartments of the face. It is generally considered when age-related changes in facial support contribute to hollowing, flattening or softer contours around the cheek and preauricular area.

Unlike traditional dermal fillers, Profhilo Structura is not primarily intended to create sharply defined contours or add substantial projected volume. Its formulation and placement are designed to integrate within facial tissue and provide subtle structural support.

Profhilo Structura is different from the standard Profhilo treatment, which focuses more broadly on skin hydration, elasticity and laxity. A face-to-face assessment is needed to determine which treatment approach, if any, is appropriate.

Profhilo Structura

What does Profhilo Structura do?

Profhilo Structura is designed for placement within selected superficial facial fat compartments. Its purpose is to support tissue affected by age-related changes rather than simply hydrate the surface of the skin.

Depending on the person’s anatomy and treatment plan, the intended changes may include:

  • Better support through the lateral cheek

  • A less hollow appearance in selected areas

  • Softer transitions between facial regions

  • Subtle improvement in facial balance

  • A refreshed appearance without pronounced projection

The treatment does not replace surgical lifting and is not intended to produce the same sculpting effect as a conventional dermal filler. Results and suitability vary.

Profhilo Structura results

Profhilo Structura results are usually intended to look subtle. The aim is to support selected facial tissues while preserving the person’s natural proportions.

Before treatment concern

Possible treatment aim

Hollowing near the lateral cheek

Better tissue support

Flattening around the preauricular area

A softer, more supported transition

Early age-related facial deflation

Subtle improvement in facial balance

Reduced definition through the mid-face

More harmonious contours

Softer lower-face appearance

Indirect improvement following lateral support

The exact result depends on facial anatomy, the degree and location of tissue change, the injection technique and the treatment plan. Profhilo Structura is not intended to create dramatic or identical results for every patient.

Profhilo Structura

How does Profhilo Structura work?

Profhilo Structura contains cooperative complexes of high- and low-molecular-weight hyaluronic acid. The formulation has different properties from standard Profhilo and from traditional cross-linked dermal fillers.

It is placed in selected superficial facial fat compartments, commonly using a cannula. The treatment is intended to integrate with the treated tissue and support areas affected by age-related changes in facial fat.

Rather than building a defined shape or projecting a specific feature, Profhilo Structura generally aims for a gradual and natural-looking improvement in facial support.

View Profhilo before and after photos to understand why results must be compared carefully and under consistent photographic conditions.

Which areas can be treated with Profhilo Structura?

Profhilo Structura is primarily associated with selected superficial facial fat compartments rather than general treatment of every facial area.

Areas that may be assessed include:

  • The lateral cheek

  • The preauricular area in front of the ear

  • Selected parts of the mid-face

  • Areas affected by early facial deflation

  • Areas where reduced tissue support contributes to softer contours

It should not automatically be treated as a jawline filler, cheekbone filler or under-eye treatment. The appropriate placement depends on the patient’s anatomy and must be determined by an experienced practitioner.

Profhilo Structura before and after

Before-and-after photographs may show changes in the lateral cheek, facial transitions and overall tissue support. These changes are generally more subtle than the projected volume commonly associated with dermal fillers.

When assessing photographs, check:

  • Whether the lighting and camera position are consistent

  • Whether the facial expression is the same

  • How long after treatment the second photograph was taken

  • Whether one or several sessions were completed

  • Whether another treatment was performed at the same time

  • Whether the concern shown resembles your own

Photographs illustrate individual outcomes and cannot predict another person’s result.

Before and after photos of Profhilo Structura

Profhilo picture of Prof. Aesthetics (before)
Profhilo picture of Prof. Aesthetics (after)
These pictures are from Prof. Aesthetics
Profhilo picture of Beautifier Maastricht (before)
Profhilo picture of Beautifier Maastricht (after)
These pictures are from Beautifier Maastricht
Profhilo picture of Moerman Clinic (before)
Profhilo picture of Moerman Clinic (after)
These pictures are from Moerman Clinic
Profhilo picture of Huidkliniek Twente (before)
Profhilo picture of Huidkliniek Twente (after)
These pictures are from Huidkliniek Twente
Profhilo picture of SkinSurgery Clinics Den Haag (before)
Profhilo picture of SkinSurgery Clinics Den Haag (after)
These pictures are from SkinSurgery Clinics Den Haag
Profhilo picture of Dikrama Clinics (before)
Profhilo picture of Dikrama Clinics (after)
These pictures are from Dikrama Clinics

Profhilo Structura vs fillers

Profhilo Structura and dermal fillers are both injectable hyaluronic acid treatments, but they have different formulations, placement strategies and treatment goals.

Treatment

Primary focus

Typical treatment aim

Standard Profhilo

Skin quality and laxity

Hydration and broader bioremodelling

Profhilo Structura

Selected superficial facial fat compartments

Subtle tissue support

Dermal fillers

Shape, projection or volume replacement

Contouring or targeted volume restoration

Profhilo Structura may be considered when the treatment goal is subtle support rather than pronounced contouring. Dermal fillers may be more appropriate when a defined feature, projection or targeted volume replacement is wanted.

Read the full comparison of Profhilo and fillers for the broader differences between these treatment categories.

Who may be suitable for Profhilo Structura?

Profhilo Structura may be considered for adults whose facial assessment shows age-related changes in selected superficial fat compartments.

Relevant concerns may include:

  • Hollowing around the lateral cheek

  • Flattening near the preauricular area

  • Early facial deflation

  • Loss of support through selected mid-face areas

  • A preference for subtle rather than highly projected results

It may be less appropriate when the main goal is:

  • Significant facial reshaping

  • Strong cheekbone projection

  • Correction of deep folds with targeted volume

  • Treatment of an unrelated skin condition

  • A surgical degree of lifting

Suitability depends on medical history, facial anatomy, previous treatments and expectations. It should be assessed during an in-person consultation.

Profhilo Structura

Is there a typical age for Profhilo Structura?

There is no single recommended age for Profhilo Structura. Treatment should be based on facial anatomy and the type of tissue change present, not on reaching a particular birthday.

Some adults develop visible changes in facial fat distribution earlier than others. Genetics, weight changes, ageing, lifestyle and previous treatments can all influence facial appearance.

How does a Profhilo Structura treatment work?

  1. 1 Consultation and facial assessment
  2. 2 Discussion of treatment goals
  3. 3 Treatment with injections or cannula
  4. 4 Aftercare advice
  5. 5 Follow-up if required

When will you see Profhilo Structura results?

Some change may be visible soon after treatment because product has been placed within the tissue. The appearance can then evolve as early swelling settles and the treatment integrates.

Published clinical protocols have commonly involved two sessions approximately one month apart, but this should not be interpreted as the correct schedule for every patient. The practitioner should determine the number and spacing of sessions.

Final assessment is usually more meaningful after the planned treatment course has been completed and temporary reactions have resolved.

For a broader explanation of treatment timelines, see when Profhilo results become visible.

How long do Profhilo Structura results last?

The duration of Profhilo Structura results varies. Published studies have followed treatment outcomes for several months, including follow-up periods of up to six months, but this does not mean every patient will receive the same duration.

Longevity may be affected by:

  • Facial anatomy

  • The degree of tissue change

  • The treatment plan

  • Metabolism

  • Ageing

  • Weight changes

  • Lifestyle

  • Previous or combined treatments

A practitioner may recommend reassessment or maintenance treatment, but this should be based on the individual result rather than a fixed timetable.

Profhilo Structura recovery timeline

Time after treatment

What may occur

First 24 hours

Redness, tenderness, swelling or localised marks

First few days

Bruising or sensitivity may remain visible

Within approximately one week

Most mild reactions should be improving

Following weeks

The result can be assessed as swelling settles and treatment effects develop

Recovery differs between patients. The injection technique, treatment area, tendency to bruise and individual healing response can all affect the timeline.

Contact the treating practitioner when symptoms are severe, worsening or different from the aftercare information provided.

Recovery after Profhilo Structura

Temporary injection-site reactions can occur after Profhilo Structura. These may include:

  • Swelling

  • Redness

  • Tenderness

  • Bruising

  • Localised firmness

  • Temporary unevenness while swelling settles

Follow the personalised instructions given by the treating practitioner. General advice may include avoiding strenuous exercise, excessive heat, alcohol and pressure on the treated area for the period advised by the clinic.

Do not massage or manipulate the area unless specifically instructed.

Seek prompt medical advice for severe or increasing pain, unusual skin discolouration, rapidly worsening swelling, signs of infection, visual symptoms or any reaction that causes concern.

Read the dedicated Profhilo aftercare guide for general post-treatment considerations.

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Profhilo Structura side effects and risks

All injectable treatments involve potential side effects and complications.

Common temporary reactions may include:

  • Redness

  • Swelling

  • Bruising

  • Tenderness

  • Localised firmness

  • Temporary asymmetry caused by swelling

Less common but potentially serious complications can include infection, inflammatory reactions, prolonged swelling and vascular complications. Injectable treatments around the face must therefore be carried out by an appropriately qualified practitioner who can recognise and manage complications.

Seek urgent assessment for severe or worsening pain, pale or mottled skin, marked discolouration, visual disturbance or other unexpected symptoms.

Learn more about general injectable reactions on the Profhilo side effects page.

How much does Profhilo Structura cost?

Profhilo Structura prices vary between UK clinics. The total cost may depend on:

  • The practitioner carrying out the treatment

  • Clinic location

  • The number of sessions recommended

  • The treatment plan

  • Whether review appointments are included

  • Whether another treatment is performed separately

When comparing prices, check whether the amount shown covers one session or a complete proposed course. A lower advertised price may not include consultation, review or additional treatment.

Compare published clinic information on the Profhilo cost comparison page. Do not choose an injectable treatment based on price alone.

Reviews of Profhilo Structura in the UK

Fabulous facial with Claire today in her new clinic space. The whole experience was incredibly relaxing and my skin feels amazing afterwards. Would 100% recommend!
Laura Crowther
WinterSkin Aesthetics
21 July 2026 19:07
Claire was extremely professional and knowledgeable with a friendly and welcoming approach. Her clinic is extremely relaxing and inviting and I was made to feel at ease the second I walked through the door in a comfortable and calm environment. The treatment itself (microneedling) has done wonders for my skin and I truly feel amazing. I would highly recommen... Show more »
Claire was extremely professional and knowledgeable with a friendly and welcoming approach. Her clinic is extremely relaxing and inviting and I was made to feel at ease the second I walked through the door in a comfortable and calm environment. The treatment itself (microneedling) has done wonders for my skin and I truly feel amazing. I would highly recommend Claire and I will be returning in the near future as I'm so happy with the results. Show less »
21 July 2026 19:07
Claire at Winterskin is amazing! I couldn’t be happier with my treatment. She’s so knowledgeable and really takes the time to walk you through everything, making you feel relaxed and in safe hands. I’m so glad I chose her and would highly recommend!
Chelsie Gilbert
WinterSkin Aesthetics
21 July 2026 19:07
I would trust absolutely nobody else with my face, Claire is amazing. I have had a severe needle phobia since being 13 and always wanted to have Botox due to my forehead being a massive insecurity. Claire made me feel so comfortable and relaxed I was able to overcome my fear for the first time!! Stunning clinic and a beautiful lady.
21 July 2026 19:07
Clare is an absolutely wonderful practitioner. I wouldn't trust my face with anyone else!!!
21 July 2026 17:05
I have undergone a number of treatments with excellent results. Dr Raquel has always taken lots of time to explain treatments. She is also incredibly knowledgeable about the products she uses and how they will work on your skin. I have huge trust in her, which is so important when having injectable products
14 July 2026 21:09

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Frequently asked questions about Profhilo Structura

What is Profhilo Structura?

Is Profhilo Structura a filler?

Does Profhilo Structura add volume?

Which areas can be treated?

How quickly will I see results?

How long do results last?

Is the treatment painful?

Is Profhilo Structura safe?

Can Profhilo Structura be combined with fillers?

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