
Profhilo Structura is an injectable hyaluronic acid treatment developed for selected superficial fat compartments of the face. It is generally considered when age-related changes in facial support contribute to hollowing, flattening or softer contours around the cheek and preauricular area.
Unlike traditional dermal fillers, Profhilo Structura is not primarily intended to create sharply defined contours or add substantial projected volume. Its formulation and placement are designed to integrate within facial tissue and provide subtle structural support.
Profhilo Structura is different from the standard Profhilo treatment, which focuses more broadly on skin hydration, elasticity and laxity. A face-to-face assessment is needed to determine which treatment approach, if any, is appropriate.

Profhilo Structura is designed for placement within selected superficial facial fat compartments. Its purpose is to support tissue affected by age-related changes rather than simply hydrate the surface of the skin.
Depending on the person’s anatomy and treatment plan, the intended changes may include:
Better support through the lateral cheek
A less hollow appearance in selected areas
Softer transitions between facial regions
Subtle improvement in facial balance
A refreshed appearance without pronounced projection
The treatment does not replace surgical lifting and is not intended to produce the same sculpting effect as a conventional dermal filler. Results and suitability vary.
Profhilo Structura results are usually intended to look subtle. The aim is to support selected facial tissues while preserving the person’s natural proportions.
Before treatment concern | Possible treatment aim |
|---|---|
Hollowing near the lateral cheek | Better tissue support |
Flattening around the preauricular area | A softer, more supported transition |
Early age-related facial deflation | Subtle improvement in facial balance |
Reduced definition through the mid-face | More harmonious contours |
Softer lower-face appearance | Indirect improvement following lateral support |
The exact result depends on facial anatomy, the degree and location of tissue change, the injection technique and the treatment plan. Profhilo Structura is not intended to create dramatic or identical results for every patient.

Profhilo Structura contains cooperative complexes of high- and low-molecular-weight hyaluronic acid. The formulation has different properties from standard Profhilo and from traditional cross-linked dermal fillers.
It is placed in selected superficial facial fat compartments, commonly using a cannula. The treatment is intended to integrate with the treated tissue and support areas affected by age-related changes in facial fat.
Rather than building a defined shape or projecting a specific feature, Profhilo Structura generally aims for a gradual and natural-looking improvement in facial support.
View Profhilo before and after photos to understand why results must be compared carefully and under consistent photographic conditions.
Profhilo Structura is primarily associated with selected superficial facial fat compartments rather than general treatment of every facial area.
Areas that may be assessed include:
The lateral cheek
The preauricular area in front of the ear
Selected parts of the mid-face
Areas affected by early facial deflation
Areas where reduced tissue support contributes to softer contours
It should not automatically be treated as a jawline filler, cheekbone filler or under-eye treatment. The appropriate placement depends on the patient’s anatomy and must be determined by an experienced practitioner.
Before-and-after photographs may show changes in the lateral cheek, facial transitions and overall tissue support. These changes are generally more subtle than the projected volume commonly associated with dermal fillers.
When assessing photographs, check:
Whether the lighting and camera position are consistent
Whether the facial expression is the same
How long after treatment the second photograph was taken
Whether one or several sessions were completed
Whether another treatment was performed at the same time
Whether the concern shown resembles your own
Photographs illustrate individual outcomes and cannot predict another person’s result.












Profhilo Structura and dermal fillers are both injectable hyaluronic acid treatments, but they have different formulations, placement strategies and treatment goals.
Treatment | Primary focus | Typical treatment aim |
Standard Profhilo | Skin quality and laxity | Hydration and broader bioremodelling |
Profhilo Structura | Selected superficial facial fat compartments | Subtle tissue support |
Dermal fillers | Shape, projection or volume replacement | Contouring or targeted volume restoration |
Profhilo Structura may be considered when the treatment goal is subtle support rather than pronounced contouring. Dermal fillers may be more appropriate when a defined feature, projection or targeted volume replacement is wanted.
Read the full comparison of Profhilo and fillers for the broader differences between these treatment categories.
Profhilo Structura may be considered for adults whose facial assessment shows age-related changes in selected superficial fat compartments.
Relevant concerns may include:
Hollowing around the lateral cheek
Flattening near the preauricular area
Early facial deflation
Loss of support through selected mid-face areas
A preference for subtle rather than highly projected results
It may be less appropriate when the main goal is:
Significant facial reshaping
Strong cheekbone projection
Correction of deep folds with targeted volume
Treatment of an unrelated skin condition
A surgical degree of lifting
Suitability depends on medical history, facial anatomy, previous treatments and expectations. It should be assessed during an in-person consultation.

There is no single recommended age for Profhilo Structura. Treatment should be based on facial anatomy and the type of tissue change present, not on reaching a particular birthday.
Some adults develop visible changes in facial fat distribution earlier than others. Genetics, weight changes, ageing, lifestyle and previous treatments can all influence facial appearance.
Some change may be visible soon after treatment because product has been placed within the tissue. The appearance can then evolve as early swelling settles and the treatment integrates.
Published clinical protocols have commonly involved two sessions approximately one month apart, but this should not be interpreted as the correct schedule for every patient. The practitioner should determine the number and spacing of sessions.
Final assessment is usually more meaningful after the planned treatment course has been completed and temporary reactions have resolved.
For a broader explanation of treatment timelines, see when Profhilo results become visible.
The duration of Profhilo Structura results varies. Published studies have followed treatment outcomes for several months, including follow-up periods of up to six months, but this does not mean every patient will receive the same duration.
Longevity may be affected by:
Facial anatomy
The degree of tissue change
The treatment plan
Metabolism
Ageing
Weight changes
Lifestyle
Previous or combined treatments
A practitioner may recommend reassessment or maintenance treatment, but this should be based on the individual result rather than a fixed timetable.
Time after treatment | What may occur |
First 24 hours | Redness, tenderness, swelling or localised marks |
First few days | Bruising or sensitivity may remain visible |
Within approximately one week | Most mild reactions should be improving |
Following weeks | The result can be assessed as swelling settles and treatment effects develop |
Recovery differs between patients. The injection technique, treatment area, tendency to bruise and individual healing response can all affect the timeline.
Contact the treating practitioner when symptoms are severe, worsening or different from the aftercare information provided.
Temporary injection-site reactions can occur after Profhilo Structura. These may include:
Swelling
Redness
Tenderness
Bruising
Localised firmness
Temporary unevenness while swelling settles
Follow the personalised instructions given by the treating practitioner. General advice may include avoiding strenuous exercise, excessive heat, alcohol and pressure on the treated area for the period advised by the clinic.
Do not massage or manipulate the area unless specifically instructed.
Seek prompt medical advice for severe or increasing pain, unusual skin discolouration, rapidly worsening swelling, signs of infection, visual symptoms or any reaction that causes concern.
Read the dedicated Profhilo aftercare guide for general post-treatment considerations.





All injectable treatments involve potential side effects and complications.
Common temporary reactions may include:
Redness
Swelling
Bruising
Tenderness
Localised firmness
Temporary asymmetry caused by swelling
Less common but potentially serious complications can include infection, inflammatory reactions, prolonged swelling and vascular complications. Injectable treatments around the face must therefore be carried out by an appropriately qualified practitioner who can recognise and manage complications.
Seek urgent assessment for severe or worsening pain, pale or mottled skin, marked discolouration, visual disturbance or other unexpected symptoms.
Learn more about general injectable reactions on the Profhilo side effects page.
Profhilo Structura prices vary between UK clinics. The total cost may depend on:
The practitioner carrying out the treatment
Clinic location
The number of sessions recommended
The treatment plan
Whether review appointments are included
Whether another treatment is performed separately
When comparing prices, check whether the amount shown covers one session or a complete proposed course. A lower advertised price may not include consultation, review or additional treatment.
Compare published clinic information on the Profhilo cost comparison page. Do not choose an injectable treatment based on price alone.








Profhilo Structura is a hyaluronic acid injectable designed to support skin quality, firmness and facial contours.
No. It is different from traditional dermal fillers and focuses on skin quality and structural support rather than significant volume enhancement.
It may provide subtle volume support, but it is not intended to create the same volumising effect as fillers.
Common areas include the cheeks, mid-face, jawline and areas affected by volume loss or reduced facial definition.
Some improvements may become noticeable within a few weeks, with further changes developing gradually over time.
Results are often visible for around 4 to 6 months, although this varies between individuals.
Most people tolerate treatment well, although mild discomfort or pressure may be experienced during injections.
All injectable treatments carry risks. A consultation with an experienced practitioner can help determine whether the treatment is suitable for you.
Yes. Some practitioners combine Profhilo Structura with fillers or other injectable treatments as part of an individual treatment plan.
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